Uveal Blood Flow Determined by the Nitrous Oxide Method.

Theoretic limitations of the nitrous oxide method for the determination of regional blood flow.

The nitrous oxide method for regional blood flow determination is based on the assumption that concentration equilibrium for nitrous oxide between the organ and its venous blood is reached. This assumption is examined, and it is shown mathematically that faulty equilibrium is not revealed by presently available criteria. It is shown that quantitatively and qualitatively erroneous results may li...

Nitric oxide as a mediator of parasympathetic vasodilation in ocular and extraocular tissues in the rabbit.

PURPOSE The aim of this study was to investigate in rabbits the relationship between nitric oxide and the noncholinergic vasodilation caused by facial nerve stimulation in the eye and some extraocular tissues. METHODS Uveal vascular resistance was determined by measuring simultaneously the flow from a cannulated vortex vein with intraocular pressure and arterial blood pressure recordings. The...

The solubility of nitrous oxide in blood and brain.

Since the formulation of the lipide theory of anesthesia (1) there has been some interest in the solubilities of various volatile anesthetics in the brain (2-6). Unfortunately the results obtained in viva have been equivocal and inexact because of the technical difficulties of obtaining -and analyzing without loss samples of brain containing volatile gas. Even the studies on solubility in vitro...

A comparison of coronary flow determined by the nitrous oxide method and by a direct method using the rotameter.

Measurement of coronary blood flow in dogs and man from rate of myocardial nitrous oxide desaturation.

A technic of measuring left ventricular coronary blood flow in dogs and man from the rate of desaturation of nitrous oxide from the myocardium is presented. The desaturation technic appears valid in comparison with the previously described saturation technic, and affords definite technical advantages. By combining the two technics, flows may be measured within much less time than by repeating e...